太原在哪里哪里能购买到少量的盐酸苯肼?

Phenylhydrazine hydrochloride
C6H8N2·HCl
分子量144.60
Beilstein号
EC号 200-444-7
MDL号 MFCD
PubChem编号
组合的产品项目
上海(预计3-7周)北方(预计3-7周)
上海(>10)北方(>10)
上海(预计3-7周)北方(4)
添加到购物车
对光,空气和湿度敏感
243-246°C
溶于水(50 mg/ml)和乙醇,不溶于醚。
对光和湿敏感。能升华。易溶于水,溶于乙醇,几乎不溶于乙醚。加入浓盐酸则从溶液中析出沉淀。有毒,最小致死量(兔,经口)25mg/kg。有致癌可能性。
苯肼盐酸盐;苯基联氨盐酸盐;肼基苯盐酸盐;苯肼单盐酸盐;Phenylhydrazinium chloride
Phenylhydrazine hydrochloride causes acute hemolysis when injected intraperitoneally in to wild-type and Hp and Hx single-null mice. It suppresses the horseradish peroxide (HRP) residual activity in tissue sections of animals.
醛、酮和糖的特殊试剂。主要用于合成农药、医药、染料及合成其它有机物。
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风险声明 (欧洲)
安全声明(欧洲)
警示性声明
危害码(欧洲)
个人防护设备
Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Merck Index
Alterations in bone and erythropoiesis in hemolytic anemia: comparative study in bled, phenylhydrazine-treated and Plasmodium-infected mice.
Robert Moreau, Diane Tshikudi Malu, Mathieu Dumais, Esther Dalko, Véronique Gaudreault, Hugo Roméro, Corine Martineau, Olha Kevorkova, Jaime Sanchez Dardon, Erin Lynn Dodd, David Scott Bohle, Tatiana Scorza
Sustained erythropoiesis and concurrent bone marrow hyperplasia are proposed to be responsible for low bone mass density (BMD) in chronic hemolytic pathologies. As impaired erythropoiesis is also freq...
Transfection of rodent malaria parasites.
Nisha Philip, Rachael Orr, Andrew P Waters
Gene manipulation is an invaluable tool to investigate and understand the biology of an organism. Although this technology has been applied to both the human and rodent malarial parasites (RMP), Plasm...
Reductive deprotonation and dehydrogenation of phenylhydrazine at a nickel center to give a nickel diazenido complex.
Claudia K?the, Ramona Metzinger, Christian Herwig, Christian Limberg
The reaction of [L(tBu)Ni(OEt(2))] (where L(tBu) = [HC(C(t)BuNC(6)H(3)((i)Pr)(2))(2)](-)) with phenylhydrazine leads to the phenylhydrazido(1-) complex [L(tBu)Ni(η(2)-NPhNH(2))] (1) with concomitant ...
ROCK1 functions as a critical regulator of stress erythropoiesis and survival by regulating p53.
Sasidhar Vemula, Jianjian Shi, Raghuveer Singh Mali, Peilin Ma, Yan Liu, Philip Hanneman, Karl R Koehler, Eri Hashino, Lei Wei, Reuben Kapur
Erythropoiesis is a dynamic, multistep process whereby hematopoietic stem cells differentiate toward a progressively committed erythroid lineage through intermediate progenitors. Although several down...
Hematopoietic effect of Bacillus subtilis-fermented antler extract on phenylhydrazine-induced hemolytic anemia in Sprague-Dawley rats.
Sang Hun Lee, Hyung Joo Suh, Hyun-Sun Lee, Yooheon Park, Jang-Woo Park, Eun Young Jung
This study examined the effect of fermentation on the ability of antler to act as a stimulator of hematopoietic activity. Hemolytic anemia was induced by phenylhydrazine (PHZ) in female Sprague-Dawley...
Novel antimicrobial organic thermal stabilizer and co-stabilizer for rigid PVC.
Mona M MM Fahmy, Riham R RR Mohamed, Nadia A NA Mohamed
Biologically active N-benzoyl-4-(N-maleimido)-phenylhydrazide (BMPH) was synthesized and its structure was confirmed by elemental analysis and various spectral tools. It was examined as a thermal stab...
Cardiac remodelling of Atlantic halibut Hippoglossus hippoglossus induced by experimental anaemia with phenylhydrazine.
M D MD Powell, M S MS Burke, D D Dahle
Phenylhydrazine injections (0.3 mg kg(-1) , followed by a second injection of 0.1 mg kg(-1) 7 days later) induced a reproducible and stable anaemia in Atlantic halibut Hippoglossus hippoglossus, reduc...
Growth and properties of Ag-doped ZnO nanoflowers for highly sensitive phenyl hydrazine chemical sensor application.
Ahmed A AA Ibrahim, G N GN Dar, Shabi Abbas SA Zaidi, Ahmad A Umar, M M Abaker, H H Bouzid, S S Baskoutas
We report here the fabrication of a robust, highly sensitive, reliable and reproducible phenyl hydrazine chemical sensor using Ag-doped ZnO nanoflowers as efficient electron mediators. The Ag-doped Zn...
Stimulated erythropoiesis with secondary iron loading leads to a decrease in hepcidin despite an increase in bone morphogenetic protein 6 expression.
David M DM Frazer, Sarah J SJ Wilkins, Deepak D Darshan, Alison C AC Badrick, Gordon D GD McLaren, Gregory J GJ Anderson
The BMP/SMAD signalling pathway plays an important role in iron homeostasis, regulating hepcidin expression in response to body iron levels. However, the role of this pathway in the reduction in hepci...
Defective erythroid maturation in gelsolin mutant mice.
Claudio Cantù, Francesca Bosè, Paola Bianchi, Eva Reali, Maria Teresa Colzani, Ileana Cantù, Gloria Barbarani, Sergio Ottolenghi, Walter Witke, Laura Spinardi, Antonella Ellena Ronchi
During late differentiation, erythroid cells undergo profound changes involving actin filament remodeling. One of the proteins controlling actin dynamics is gelsolin, a calcium-activated actin filamen...
Malaria impairs resistance to Salmonella through heme- and heme oxygenase-dependent dysfunctional granulocyte mobilization.
Aubrey J Cunnington, J Brian de Souza, Michael Walther, Eleanor M Riley
In sub-Saharan Africa, invasive nontyphoid Salmonella (NTS) infection is a common and often fatal complication of Plasmodium falciparum infection. Induction of heme oxygenase-1 (HO-1) mediates toleran...
Synthesis and antibacterial activity of a new series of 3-[3-(substituted phenyl)-1-phenyl-1H-pyrazol-5-yl]-2H-chromen-2-one derivatives.
Prashant Aragade, R Venkat Narayanan, Veeresh Maddi, Pankaj Patil, Prashant Shinde, Mohan Agrawal
A series of 3-[3-(substituted phenyl)-1-phenyl-1H-pyrazol-5-yl]-2H-chromen-2-one (4a-k) were synthesized by reaction of 3-[2,3-dibromo-3-(substituted phenyl)propanoyl]-2H-chromen-2-one (3 a-k) with ph...
Trpc2 depletion protects red blood cells from oxidative stress-induced hemolysis.
Iwona Hirschler-Laszkiewicz, Wenyi Zhang, Kerry Keefer, Kathleen Conrad, Qin Tong, Shu-jen Chen, Sarah Bronson, Joseph Y Cheung, Barbara A Miller
Transient receptor potential (TRP) channels Trpc2 and Trpc3 are expressed on normal murine erythroid precursors, and erythropoietin stimulates an increase in intracellular calcium ([Ca(2+)](i)) throug...
Anaemia adjusts the aerobic physiology of snapper (Pagrus auratus) and modulates hypoxia avoidance behaviour during oxygen choice presentations.
Denham G DG Cook, Rufus M G RM Wells, Neill A NA Herbert
The effect of altered oxygen transport potential on behavioural responses to environmental hypoxia was tested experimentally in snapper, Pagrus auratus, treated with a haemolytic agent (phenylhydrazin...
Rapid clearance of transfused murine red blood cells is associated with recipient cytokine storm and enhanced alloimmunogenicity.
Jeanne E Hendrickson, Eldad A Hod, Chantel M Cadwell, Stephanie C Eisenbarth, David A Spiegel, Christopher A Tormey, Steven L Spitalnik, James C Zimring
Fourteen-day stored red blood cells (RBCs) containing an RBC-specific transgenic antigen (HOD) induce a recipient proinflammatory cytokine storm and are significantly more immunogenic compared to fres...
Energy production and redox status of rat red blood cells after reticulocytosis induced by various treatments.
Sne?ana D SD Markovi?, Jovana B JB Zi?i?, Ana D AD Obradovi?, Branka I BI Ognjanovi?, A S AS Stajn, Zorica S ZS Sai?i?, M B MB Spasi?
Stimulated erythropoiesis and reticulocytosis can be induced by daily bleeding, or by phenylhydrazine (PHZ) treatment. We compared the in vivo effects of PHZ and bleeding treatment on haematological, ...
A novel acetate selective chromogenic chemosensor based on phenanthroline
Weiwei Huang, Yaping Li, Zhongyue Yang, Hai Lin, Huakuan Lin
A novel colorimetric anion-chemosensor based on 1,10-phenanthroline-2,9-dicarbonyl-p-nitro-phenylhydrazine has been synthesized. Among the different anions tested, it shows the best selectivity toward...
The oxidation of phenylhydrazine by tyrosinase.
Yi-Ming Sung, Srivardhan Reddy Gayam, Shu-Pao Wu
Tyrosinase was found to catalyze the oxidation of phenylhydrazine to phenol in a reaction that did not resemble those typically performed by tyrosinase. The kinetics of this reaction was investigated ...
A novel hemoglobin-binding peptide reduces cell-free hemoglobin in murine hemolytic anemia.
Madelyn S Hanson, Hao Xu, Timothy C Flewelen, Sandra L Holzhauer, Dawn Retherford, Deron W Jones, Anne C Frei, Kirkwood A Pritchard, Cheryl A Hillery, Neil Hogg, Nancy J Wandersee
Hemolysis can saturate the hemoglobin (Hb)/heme scavenging system, resulting in increased circulating cell-free Hb (CF-Hb) in hereditary and acquired hemolytic disease. While recent studies have sugge...
Hepatic extramedullary hematopoiesis and macrophages in the adult mouse: histometrical and immunohistochemical studies.
Yuji Sonoda, Kazunobu Sasaki
Fetal liver hematopoiesis in mice disappears approximately 2 however, under experimental acute anemia extramedullary hematopoiesis occurs in the livers of adult mice. The hematopoie...
Iron metabolism in hepcidin1 knockout mice in response to phenylhydrazine-induced hemolysis.
Patarabutr P Masaratana, Gladys O GO Latunde-Dada, Neeta N Patel, Robert J RJ Simpson, Sophie S Vaulont, Andrew T AT McKie
Hepcidin, an iron regulatory peptide, plays a central role in the maintenance of systemic iron homeostasis by inducing the internalization and degradation of the iron exporter, ferroportin. Hepcidin e...
Synthesis and bioactivity of pyrazole acyl thiourea derivatives.
Jian J Wu, Qing Q Shi, Zhuo Z Chen, Ming M He, Linhong L Jin, Deyu D Hu
Sixteen novel pyrazole acyl thiourea derivatives 6 were synthesized from monomethylhydrazine (phenylhydrazine) and ethyl acetoacetate. The key 5-chloro-3-methyl-1-substituted-1H-pyrazole-4-carbonyl ch...
ATP-dependent mitochondrial porphyrin importer ABCB6 protects against phenylhydrazine toxicity.
Dagny L Ulrich, John Lynch, Yao Wang, Yu Fukuda, Deepa Nachagari, Guoqing Du, Daxi Sun, Yiping Fan, Lyudmila Tsurkan, Philip M Potter, Jerold E Rehg, John D Schuetz
Abcb6 is a mammalian mitochondrial ATP-binding cassette (ABC) transporter that regulates de novo porphyrin synthesis. In previous studies, haploinsufficient (Abcb6(+/-)) embryonic stem cells showed im...
Comparative proteomics reveals deficiency of NHE-1 (Slc9a1) in RBCs from the beta-adducin knockout mouse model of hemolytic anemia.
Diana M DM Gilligan, Greg L GL Finney, Eric E Rynes, Michael J MJ Maccoss, Amy J AJ Lambert, Luanne L LL Peters, Raymond F RF Robledo, Jason M JM Wooden
Hemolytic anemia is one of the most common inherited disorders. To identify candidate proteins involved in hemolytic anemia pathophysiology, we utilized a label-free comparative proteomic approach to ...
Plasmodium vinckei: infectivity of arteether-sensitive and arteether-resistant parasites in different strains of mice.
Ramesh R Chandra, Santosh S Kumar, S K SK Puri
Malaria is one of the most lethal parasitic infections in the world. The lethality of the parasite depends on the rate of multiplication of the parasite within host erythrocytes. Different strains of ...
Erythropoietin and Friend virus gp55 activate different JAK/STAT pathways through the erythropoietin receptor in erythroid cells.
Y Yamamura, H Senda, Y Kageyama, T Matsuzaki, M Noda, Y Ikawa
Abnormal erythropoietin (EPO)-independent cell growth is induced after infection of erythroid progenitor cells with a polycythemic strain of Friend virus (FVp). Binding of its Env-related glycoprotein...
Enhanced splenomegaly and severe liver inflammation in haptoglobin/hemopexin double-null mice after acute hemolysis.
Emanuela E Tolosano, Sharmila S Fagoonee, Emilio E Hirsch, Franklin G FG Berger, Heinz H Baumann, Lorenzo L Silengo, Fiorella F Altruda
Intravascular hemolysis is associated with several pathologic conditions that include hemoglobinopathies, trauma, malaria, and bacterial infections. Among plasma-protective proteins against oxidative ...
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